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Oak Street Medical Blog

From the Shehzad Jinnah, M.D. blog

What is pertussis? Whooping cough, and it’s preventable

Print Posted by Shehzad Jinnah, M.D. in Primary Care


Are you at risk for developing whooping cough, also known as pertussis? You may be unaware that the incidence of this illness has increased in both Oregon and the nation. However, you can prevent it with improved vaccinations and boosters.

Background
The name pertussis (intense cough) was first coined by Thomas Sydenham in 1670. The name pertussis is preferable to whooping cough because most infected individuals do not "whoop." The cause of the illness is a toxin, produced by a bacterium called Bordetella Pertussis that is found in the mouth, nose and throat of an infected person. Pertussis can occur at any age. In Oregon, from 2000 through 2010, approximately 60 percent of the pertussis patients were 10 years of age or older. Hospitalization and death from pertussis (4 in the past 5 years) have been limited to those under 1 year of age.

Symptoms
Early symptoms frequently include a runny nose and low-grade fever with a mild cough. Later, as the disease progresses, paroxysms (fits) of coughing occur, sometimes followed by a whooping sound as the child tries to breath. Vomiting, disturbed sleep, weight loss, incontinence, rib fractures and occasionally passing out from episodes of violent coughing can occur.

Pertussis in 2010
In 2010, 27,500 cases of pertussis were reported in the US, but many more go undiagnosed and unreported. California alone reported more than 9,000 of these cases, more than the state had seen since 1947. Of these, 89 percent occurred in infants younger than 6 months, a group too young to be adequately immunized and largely dependent on herd immunity for protection from infection. Ten of these infants died from their infection.

Vaccines
Vaccines containing tetanus toxoid, diphtheria and acellular pertussis, in the form of DTaP for children between 6 weeks and 6 years of age and Tdap, available since 2006 for ages 10 through 64 and more recently for 65 and above, provide immunity against pertussis as well as diphtheria and tetanus.

Importance of vaccines
The United States saw as many as 200,000 cases of diphtheria and pertussis and hundreds of cases of tetanus before these vaccines became available. Since then, tetanus and diphtheria cases have dropped by about 99 percent and pertussis cases by 97 percent thanks to vaccinations. In fact, during the pre-vaccine era of 1922-1948, pertussis was the leading cause of death due to communicable disease among children less than 14 years of age.

The pivotal role of vaccines in disease control is reflected in the continued high incidence of pertussis in developing countries, and resurgence in other countries where vaccine coverage is low or where less potent vaccines are used. As a result, 30-50 million cases of pertussis occur worldwide each year, resulting in more than 300,000 deaths.

Today, universal pertussis immunization of children younger than 7 years of age, beginning in infancy is essential in controlling pertussis. Adult vaccination with Tdap is recommended for those who come in close contact with infants, such as grandparents, childcare and healthcare providers and pregnant women. Pregnant women who have never had a dose of Tdap, should get one after the 20th week of gestation and preferably during the third trimester.

Despite the phenomenal success of childhood vaccination, thousands of U.S. parents refuse selected vaccines or delay their administration on either religious or philosophical grounds. Others believe that the benefits of at least some immunizations don't justify the risks. Since parents today have little or no experience with vaccine-preventable diseases, such as polio, hemophilus influenza type b (Hib) or measles, they can't easily appreciate the benefits of vaccination or the risks of not vaccinating.

In this age of information or misinformation, sources such as television and the Internet spread rumors more often than facts. In my opinion, the beneficial evidence speaks for itself and is not open for debate!


Diabetes on the rise

Print Posted by Shehzad Jinnah, M.D. in Primary CareDiabetes

Every time we turn on the TV, we’re constantly reminded to stay in shape, eat right, and lead a healthy lifestyle. We see commercials for the newest low-calorie foods or shows like the "Biggest Loser."

Yet, many Americans still struggle with their weight and are diabetic or pre-diabetic. Today, an estimated 60 to 70 percent of the U.S. population is overweight, 30 percent is obese and 6 percent is morbidly obese or weighs at least 100 pounds above his or her ideal body weight. In the last two decades, the twin epidemics of obesity and diabetes have been the leading causes of poor health in the United States.

What is the difference between Type 1 and Type 2 diabetes?

You may have heard of two types of diabetes. Type 1 diabetes occurs when the pancreas has lost all capacity to produce insulin; this often occurs during youth.

Whereas, Type 2 diabetes, the most common type of diabetes in America, usually occurs in overweight adults and it is due to insulin resistance. This means that there is still some insulin present, but it does not have a normal effect on the body because off excess fat tissue. In addition, the pancreas tries to increase insulin production but cannot keep up resulting in a relative insulin deficiency. This is further complicated by increased liver glucose production. The result is a cycle of worsening diabetes and complications.

Why should I care about diabetes?

Today, diabetes is the leading cause of blindness in those 20-74 years of age. Additionally, it is the leading cause of end-stage kidney disease, and 60 percent of diabetic patients are affected by neuropathies or nerve damage.

In the United States, diabetes accounts for 50 percent of all non-traumatic amputations due to accelerated lower extremity arterial disease and neuropathy. The risk of cardiovascular complications is 2-to-6 fold greater, and the overall life expectancy is about 7-10 years shorter for a diabetic patient.

Can diabetes be reversed?

A common misconception is that all diabetes is irreversible. In the case of Type 1, this is certainly true, except for those rare instances of spontaneous remission, or after a pancreatic transplant.

But Type 2 diabetes, for the most part, is a lifestyle issue. Remission is achieved in a significant number of people undergoing bariatric surgery, or those managing to lose weight through diet and exercise. Drugs are an important part of treatment, but lifestyle choices are even more important. A person with Type 2 diabetes who reduces his or her weight by 5 to 10 percent can significantly improve glucose levels, sometimes allowing for a reduction or withdrawal of medication.

What can you do to prevent diabetes?

You can prevent diabetes through proper diet and exercise. The American Diabetes Association estimates that by the year 2050, as many as 1 in 3 American adults will have diabetes, unless we take steps to prevent it.

If you have diabetes, the physicians at Oak Street Medical are here to help you control it. We will talk with you about an appropriate plan, and can also answer questions if you are trying to prevent diabetes or you are pre-diabetic.